Brady A Riedner, PhD

Senior Scientist & Asst Director of the Wisconsin Institute for Sleep and Consciousness

Biography


Dr. Riedner is a Senior Scientist in the Department of Psychiatry at the UW School of Medicine and Public Health and an Assistant Director of Research for the Wisconsin Institute for Sleep and Consciousness. His research focuses on understanding the basic mechanisms of local sleep and consciousness using high-density EEG and translating this evolving knowledge to clinical and healthy populations across the developmental spectrum. In addition to having a broad background in both basic and clinical sleep research, he is an expert in the technical aspects of EEG data collection and analysis. He helped develop many of the advanced analytic techniques widely used in the field to characterize the dynamic behavior of neural activity during sleep, especially improvising new ways to characterize the morphology and spatiotemporal dynamics of sleep slow waves. He is also a principal, hands-on contributor to the groundbreaking development of a closed-loop system for the non-pharmacological enhancement of sleep and holds multiple patents related to this research. Dr. Riedner received his BS in Philosophy and History and his PhD in Neuroscience from UW – Madison.

Research Interests: local sleep, consciousness, EEG, slow waves, sleep enhancement

Selected Publications


Riedner BA, Goldstein MR, Plante DT, Rumble ME, Ferrarelli F, Tononi G, Benca RM. Regional Patterns of Elevated Alpha and High-Frequency Electroencephalographic Activity during Nonrapid Eye Movement Sleep in Chronic Insomnia: A Pilot Study. Sleep. 2016 Apr 1;39(4):801-12. https://doi.org/10.5665/sleep.5632

Bellesi M, Riedner BA, Garcia-Molina GN, Cirelli C, Tononi G. Enhancement of sleep slow waves: underlying mechanisms and practical consequences. Front Syst Neurosci. 2014;8:208. https://doi.org/10.3389/fnsys.2014.00208

Riedner BA, Hulse BK, Murphy MJ, Ferrarelli F, Tononi G. Temporal dynamics of cortical sources underlying spontaneous and peripherally evoked slow waves. Prog Brain Res. 2011;193:201-18. Review. https://doi.org/10.1016/B978-0-444-53839-0.00013-2

Murphy M*, Riedner BA*, Huber R, Massimini M, Ferrarelli F, Tononi G. Source modeling sleep slow waves. Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1608-13. https://doi.org/10.1073/pnas.0807933106. * co-first authors

Riedner BA, Vyazovskiy VV, Huber R, Massimini M, Esser S, Murphy M, Tononi G. Sleep homeostasis and cortical synchronization: III. A high-density EEG study of sleep slow waves in humans. Sleep. 2007 Dec;30(12):1643-57. https://doi.org/10.1093/sleep/30.12.1643